Mercoledì 3 aprile 2024 ore 16.00, presso l’Auditorium Prima Clinica Medica (Edificio 6) del Policlinico Umberto I, si terrà una conferenza dell’Accademia Medica Romana nella qualePeter D. Katsikis, Professor and Head, Department of Immunology, Erasmus MC, University Medical Center Rotterdam, parlerà sul tema: “Overcoming the obstacles faced by neoantigen cancer vaccines”.

Cancer cells arise because of DNA mutations that alter their survival and/or proliferation. These mutations, however, have the potential to generate altered or entirely new protein products that the immune system sees as foreign. These altered or new proteins are called neoantigens and can serve as targets of the immune system. Therapeutic cancer vaccines that stimulate neoantigen-specific T cells are expected to improve the efficacy of immune checkpoint therapies in cancer. However, a number of obstacles still remain to be overcome before we have vaccines that induce potent neoantigen-specific T cell immunity that can provide clinical benefit in cancer. Our laboratory has been addressing some of these obstacles and is trying to find solutions for potent neoantigen vaccines that provide protection against established tumors.

La conferenza potrà essere seguita in presenza presso la sede sopra descritta oppure in streaming sulla
piattaforma Zoom utilizzando il seguente link
https://uniroma1.zoom.us/j/92312414393?pwd=cDM2bTZ3VldoWEFjSnNJNXR6bmtJdz09
(Meeting ID: 923 1241 4393; Passcode: accademia)

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